DCT rabbit pAb
ENT-A7984
Description
| REF | ENT-A7984 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DCT rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse |
| Reactivity | Human;Rat;Mouse |
| Dilution | WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 232-304 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 59kD |
| Human Gene ID | 1638 |
| Human Swiss Prot Nº | P40126 |
| Subcellular Location | Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. . |
Other Name: L-dopachrome tautomerase (DCT;DT;EC 5.3.3.12;L-dopachrome Delta-isomerase;Tyrosinase-related protein 2;TRP-2;TRP2)
Background: catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.,