FAM48A rabbit pAb
ENT-A7962
Description
| REF | ENT-A7962 |
|---|---|
| Category | Antibody Polyclonal |
| Description | FAM48A rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 85kD |
| Human Gene ID | 55578 |
| Human Swiss Prot Nº | Q8NEM7 |
| Subcellular Location | Nucleus . |
Other Name: FAM48A C13orf19 FP757
Background: function:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.,similarity:Belongs to the FAM48 family.,subunit:Interacts with MAPK14.,tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.,