TyrRS rabbit pAb
ENT-A7937
Description
| REF | ENT-A7937 |
|---|---|
| Category | Antibody Polyclonal |
| Description | TyrRS rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000,IHC 1:50-300 ELISA 1:10000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human YARS. AA range:451-500 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 60kD |
| Human Gene ID | 8565 |
| Human Swiss Prot Nº | P54577 |
| Subcellular Location | Cytoplasm . |
Other Name: Tyrosine–tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)
Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008],