MER/TYRO3 (Phospho-Tyr753/Tyr685) rabbit pAb
ENT-A7898
Description
| REF | ENT-A7898 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MER/TYRO3 (Phospho-Tyr753/Tyr685) rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA;IHC |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human MER/TYRO3 (Phospho-Tyr753/Tyr685) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 110kD |
| Human Gene ID | 10461/7301 |
| Human Swiss Prot Nº | Q12866/Q06418 |
| Subcellular Location | Cell membrane ; Single-pass type I membrane protein . |
Other Name: MERTK MER
Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],