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MAD2L1BP rabbit pAb

MAD2L1BP rabbit pAb

ENT-A7731

Description

 

 

 

REF ENT-A7731
Category Antibody Polyclonal
Description MAD2L1BP rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen Synthesized peptide derived from MAD2L1BP . at AA range: 10-90
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 31kD
Human Gene ID 9587
Human Swiss Prot Nº Q15013
Subcellular Location Nucleus. Cytoplasm, cytoskeleton, spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.

Other Name: MAD2L1BP; CMT2; KIAA0110; MAD2L1-binding protein; Caught by MAD2 protein

Background: The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],