NFATc2IP rabbit pAb
ENT-A7473
Description
| REF | ENT-A7473 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NFATc2IP rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC |
| Reactivity | Human;Rat;Mouse;;Fish |
| Reactivity | Human;Rat;Mouse;;Fish |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 48kD |
| Human Gene ID | 84901 |
| Human Swiss Prot Nº | Q8NCF5 |
| Subcellular Location | Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. . |
Other Name: NFATC2IP; NIP45; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein
Background: function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus.,subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.,