GPT2 rabbit pAb
ENT-A7466
Description
| REF | ENT-A7466 |
|---|---|
| Category | Antibody Polyclonal |
| Description | GPT2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from GPT2 . at AA range: 190-270 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 50kD |
| Human Gene ID | 84706 |
| Human Swiss Prot Nº | Q8TD30 |
| Subcellular Location | mitochondrion,mitochondrial matrix, |
Other Name: GPT2; AAT2; ALT2; Alanine aminotransferase 2; ALT2; Glutamate pyruvate transaminase 2; GPT 2; Glutamic–alanine transaminase 2; Glutamic–pyruvic transaminase 2
Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],