TMEM185A rabbit pAb
ENT-A7451
Description
| REF | ENT-A7451 |
|---|---|
| Category | Antibody Polyclonal |
| Description | TMEM185A rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TMEM185A. AA range:290-339 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 41kD |
| Human Gene ID | 84548 |
| Human Swiss Prot Nº | Q8NFB2 |
| Subcellular Location | Cell projection, dendrite . Membrane ; Multi-pass membrane protein . |
Other Name: TMEM185A; CXorf13; FAM11A; Transmembrane protein 185A; Protein FAM11A
Background: The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5′ untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Aug 2013],