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RECK rabbit pAb

RECK rabbit pAb

ENT-A7441

Description

 

 

 

REF ENT-A7441
Category Antibody Polyclonal
Description RECK rabbit pAb
Source Rabbit
Applications IHC;IF;WB;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution WB 1:500-2000 Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human RECK. AA range:21-70
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 110kD
Human Gene ID 8434
Human Swiss Prot Nº O95980
Subcellular Location Cell membrane ; Lipid-anchor, GPI-anchor .

Other Name: RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein

Background: The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],