ATRIP (phospho Ser224) rabbit pAb
ENT-A7424
Description
| REF | ENT-A7424 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ATRIP (phospho Ser224) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser224. AA range:190-239 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 86kD |
| Human Gene ID | 84126 |
| Human Swiss Prot Nº | Q8WXE1 |
| Subcellular Location | Nucleus . Redistributes to discrete nuclear foci upon DNA damage. |
Other Name: ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein
Background: This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],