ULK1 rabbit pAb
ENT-A7418
Description
| REF | ENT-A7418 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ULK1 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:500-2000,Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from the C-terminal region of human ULK1. |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 8408 |
| Human Swiss Prot Nº | O75385 |
| Subcellular Location | Cytoplasm, cytosol . Preautophagosomal structure . Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome. . |
Other Name: ULK1; KIAA0722; Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; hATG1; Unc-51-like kinase 1
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with GABARAP and GABARAPL2.,tissue specificity:Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.,