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MMTAG2 rabbit pAb

MMTAG2 rabbit pAb

ENT-A7282

Description

 

 

 

REF ENT-A7282
Category Antibody Polyclonal
Description MMTAG2 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human MMTAG2. AA range:10-59
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 34kD
Human Gene ID 79169
Human Swiss Prot Nº Q9BU76
Subcellular Location

Other Name: MMTAG2; C1orf35; Multiple myeloma tumor-associated protein 2; hMMTAG2

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5′-CGCCCCCGC-3′. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5′-CGCCCCCGC-3′. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.