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Tenascin-X rabbit pAb

Tenascin-X rabbit pAb

ENT-A7144

Description

 

 

 

REF ENT-A7144
Category Antibody Polyclonal
Description Tenascin-X rabbit pAb
Source Rabbit
Applications IHC;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human TNXB. AA range:1761-1810
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 7148
Human Swiss Prot Nº P22105
Subcellular Location Secreted, extracellular space, extracellular matrix.

Other Name: TNXB; HXBL; TNX; TNXB1; TNXB2; XB; Tenascin-X; TN-X; Hexabrachion-like protein

Background: This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5′ and 3′ ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],