mtTFA rabbit pAb
ENT-A7110
Description
| REF | ENT-A7110 |
|---|---|
| Category | Antibody Polyclonal |
| Description | mtTFA rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse;;Bovine |
| Reactivity | Human;Rat;Mouse;;Bovine |
| Dilution | WB 1:500-2000;Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TFAM. AA range:131-180 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 22kd |
| Human Gene ID | 7019 |
| Human Swiss Prot Nº | Q00059 |
| Subcellular Location | Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . |
Other Name: TFAM; TCF6; TCF6L2; Transcription factor A; mitochondrial; mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2
Background: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer’s and Parkinson’s diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],