Cadherin-23 rabbit pAb
ENT-A6914
Description
| REF | ENT-A6914 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Cadherin-23 rabbit pAb |
| Source | Rabbit |
| Applications | IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDH23. AA range:61-110 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 64072 |
| Human Swiss Prot Nº | Q9H251 |
| Subcellular Location | Cell membrane ; Single-pass type I membrane protein . |
Other Name: CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin
Background: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013],