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USP36 rabbit pAb

USP36 rabbit pAb

ENT-A6723

Description

 

 

 

REF ENT-A6723
Category Antibody Polyclonal
Description USP36 rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human USP36. AA range:501-550
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 125kD
Human Gene ID 57602
Human Swiss Prot Nº Q9P275
Subcellular Location Nucleus, nucleolus . Cytoplasm .

Other Name: USP36; KIAA1453; Ubiquitin carboxyl-terminal hydrolase 36; Deubiquitinating enzyme 36; Ubiquitin thioesterase 36; Ubiquitin-specific-processing protease 36

Background: This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016],