NPY rabbit pAb
ENT-A6251
Description
| REF | ENT-A6251 |
|---|---|
| Category | Antibody Polyclonal |
| Description | NPY rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | IHC-p 1:100-500，WB 1:500-2000,ELISA 1:5000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NPY. AA range:45-94 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 4852 |
| Human Swiss Prot Nº | P01303 |
| Subcellular Location | Secreted. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle . |
Other Name: NPY; Pro-neuropeptide Y
Background: This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014],