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MYBPC1 rabbit pAb

MYBPC1 rabbit pAb

ENT-A6166

Description

 

 

 

REF ENT-A6166
Category Antibody Polyclonal
Description MYBPC1 rabbit pAb
Source Rabbit
Applications WB;ELISA;IHC
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen The antiserum was produced against synthesized peptide derived from human MYBPC1. AA range:218-267
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 120kD
Human Gene ID 4604
Human Swiss Prot Nº Q00872
Subcellular Location cytosol,myofibril,myosin filament,

Other Name: MYBPC1; MYBPCS; Myosin-binding protein C; slow-type; Slow MyBP-C; C-protein, skeletal muscle slow isoform

Background: This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],