A-Myb rabbit pAb
ENT-A6165
Description
| REF | ENT-A6165 |
|---|---|
| Category | Antibody Polyclonal |
| Description | A-Myb rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MYB-A. AA range:231-280 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 85kD |
| Human Gene ID | 4603 |
| Human Swiss Prot Nº | P10243 |
| Subcellular Location | Nucleus . |
Other Name: MYBL1; AMYB; Myb-related protein A; A-Myb; Myb-like protein 1
Background: function:Strong transcriptional activator; DNA-binding protein that specifically recognize the sequence 5′-YAAC[GT]G-3′. Could have a role in the proliferation and/or differentiation of neurogenic, spermatogenic and B-lymphoid cells.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.,tissue specificity:Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.,