HBP1 (phospho Ser402) rabbit pAb
ENT-A5510
Description
| REF | ENT-A5510 |
|---|---|
| Category | Antibody Polyclonal |
| Description | HBP1 (phospho Ser402) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HBP1 around the phosphorylation site of Ser402. AA range:371-420 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 58kD |
| Human Gene ID | 26959 |
| Human Swiss Prot Nº | O60381 |
| Subcellular Location | Nucleus . |
Other Name: HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1
Background: function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5′-TTCATTCATTCA-3′. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,