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SERGEF rabbit pAb

SERGEF rabbit pAb

ENT-A5481

Description

 

 

 

REF ENT-A5481
Category Antibody Polyclonal
Description SERGEF rabbit pAb
Source Rabbit
Applications WB;ELISA;IHC
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 50kD
Human Gene ID 26297
Human Swiss Prot Nº Q9UGK8
Subcellular Location Cytoplasm . Nucleus .

Other Name: SERGEF; DELGEF; GNEFR; Secretion-regulating guanine nucleotide exchange factor; Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Guanine nucleotide exchange factor-related protein

Background: function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,