DECR2 rabbit pAb
ENT-A5455
Description
| REF | ENT-A5455 |
|---|---|
| Category | Antibody Polyclonal |
| Description | DECR2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DECR2. AA range:217-266 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 36kD |
| Human Gene ID | 26063 |
| Human Swiss Prot Nº | Q9NUI1 |
| Subcellular Location | Peroxisome . |
Other Name: DECR2; PDCR; Peroxisomal 2; 4-dienoyl-CoA reductase; pDCR; 2,4-dienoyl-CoA reductase 2
Background: catalytic activity:Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH.,function:Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.,