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T2R48 rabbit pAb

T2R48 rabbit pAb

ENT-A5443

Description

 

 

 

REF ENT-A5443
Category Antibody Polyclonal
Description T2R48 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human TAS2R48. AA range:90-139
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD
Human Gene ID 259294
Human Swiss Prot Nº P59542
Subcellular Location Membrane; Multi-pass membrane protein.

Other Name: TAS2R19; TAS2R23; TAS2R48; Taste receptor type 2 member 19; Taste receptor type 2 member 23; Taste receptor type 2 member 48; T2R48

Background: function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,