Dsg2 rabbit pAb
ENT-A5081
Description
| REF | ENT-A5081 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Dsg2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 140kD |
| Human Gene ID | 1829 |
| Human Swiss Prot Nº | Q14126 |
| Subcellular Location | Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome. |
Other Name: DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC
Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],