Dynamin I (phospho Ser778) rabbit pAb
ENT-A5066
Description
| REF | ENT-A5066 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Dynamin I (phospho Ser778) rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DYN1 around the phosphorylation site of Ser778. AA range:751-800 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 100kD |
| Human Gene ID | 1759 |
| Human Swiss Prot Nº | Q05193 |
| Subcellular Location | Cytoplasm . Cytoplasm, cytoskeleton . Microtubule-associated. |
Other Name: DNM1; DNM; Dynamin-1
Background: dynamin 1(DNM1) Homo sapiens This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3′ region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],