ADAMTS-17 rabbit pAb
ENT-A5058
Description
| REF | ENT-A5058 |
|---|---|
| Category | Antibody Polyclonal |
| Description | ADAMTS-17 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from ADAMTS-17 . at AA range: 150-230 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | |
| Human Gene ID | 170691 |
| Human Swiss Prot Nº | Q8TE56 |
| Subcellular Location | Secreted, extracellular space, extracellular matrix . |
Other Name: ADAMTS17; A disintegrin and metalloproteinase with thrombospondin motifs 17; ADAM-TS 17; ADAM-TS17; ADAMTS-17
Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may promote breast cancer cell growth and survival. Mutations in this gene are associated with a Weill-Marchesani-like syndrome, which is characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. [provided by RefSeq, May 2016],