COL4A5 rabbit pAb
ENT-A4826
Description
| REF | ENT-A4826 |
|---|---|
| Category | Antibody Polyclonal |
| Description | COL4A5 rabbit pAb |
| Source | Rabbit |
| Applications | IHC;IF;WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | WB 1:500-2000 Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Collagen IV alpha5. AA range:21-70 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 160kD |
| Human Gene ID | 1287 |
| Human Swiss Prot Nº | P29400 |
| Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. |
Other Name: COL4A5; Collagen alpha-5(IV) chain
Background: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010],