Vav3 (phospho Tyr173) rabbit pAb
ENT-A4575
Description
| REF | ENT-A4575 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Vav3 (phospho Tyr173) rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173) |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 100kD |
| Human Gene ID | 10451 |
| Human Swiss Prot Nº | Q9UKW4 |
| Subcellular Location | intracellular,cytosol,plasma membrane,extracellular exosome, |
Other Name: VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],