Cdc42EP2 rabbit pAb
ENT-A4572
Description
| REF | ENT-A4572 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Cdc42EP2 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BORG1. AA range:10-59 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 28kD |
| Human Gene ID | 10435 |
| Human Swiss Prot Nº | O14613 |
| Subcellular Location | Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton . |
Other Name: CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1
Background: CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011],