GDF-3 rabbit pAb
ENT-A4480
Description
| REF | ENT-A4480 |
|---|---|
| Category | Antibody Polyclonal |
| Description | GDF-3 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 41kD |
| Human Gene ID | 9573 |
| Human Swiss Prot Nº | Q9NR23 |
| Subcellular Location | Secreted . Cytoplasm . Mainly accumulated in the cytoplasm. . |
Other Name: GDF3; Growth/differentiation factor 3; GDF-3
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],