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CD248 rabbit pAb

CD248 rabbit pAb

ENT-A4178

Description

 

 

 

REF ENT-A4178
Category Antibody Polyclonal
Description CD248 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from the Internal region of human CD248. AA range:341-390
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 80kD
Human Gene ID 57124
Human Swiss Prot Nº Q9HCU0
Subcellular Location Membrane ; Single-pass type I membrane protein .

Other Name: CD248; CD164L1; TEM1; Endosialin; Tumor endothelial marker 1; CD248

Background: function:May play a role in tumor angiogenesis.,online information:Endosialin,PTM:May be N-glycosylated.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.,