Actin-α cardiac muscle rabbit pAb
ENT-A4044
Description
| REF | ENT-A4044 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Actin-α cardiac muscle rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from Actin-α cardiac muscle . at AA range: 1-80 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 42kD |
| Human Gene ID | 70 |
| Human Swiss Prot Nº | P68032 |
| Subcellular Location | Cytoplasm, cytoskeleton. |
Other Name: ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin
Background: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008],