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DNA Pol μ rabbit pAb

DNA Pol μ rabbit pAb

ENT-A4041

Description

 

 

 

REF ENT-A4041
Category Antibody Polyclonal
Description DNA Pol μ rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Rat;Mouse;
Reactivity Human;Rat;Mouse;
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen Synthesized peptide derived from DNA Pol μ . at AA range: 210-290
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 54kD
Human Gene ID 27434
Human Swiss Prot Nº Q9NP87
Subcellular Location Nucleus .

Other Name: POLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; Terminal transferase

Background: catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,