VEGF-B rabbit pAb
ENT-A3911
Description
| REF | ENT-A3911 |
|---|---|
| Category | Antibody Polyclonal |
| Description | VEGF-B rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human VEGFB. AA range:91-140 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 21kD |
| Human Gene ID | 7423 |
| Human Swiss Prot Nº | P49765 |
| Subcellular Location | Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. |
Other Name: VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
Background: This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011],