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TRP2 rabbit pAb

TRP2 rabbit pAb

ENT-A3865

Description

 

 

 

REF ENT-A3865
Category Antibody Polyclonal
Description TRP2 rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human DCT. AA range:51-100
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 60kD
Human Gene ID 1638
Human Swiss Prot Nº P40126
Subcellular Location Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .

Other Name: DCT; TYRP2; L-dopachrome tautomerase; DCT; DT; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2

Background: catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.,