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TIEG2 rabbit pAb

TIEG2 rabbit pAb

ENT-A3825

Description

 

 

 

REF ENT-A3825
Category Antibody Polyclonal
Description TIEG2 rabbit pAb
Source Rabbit
Applications WB;IHC;IF;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human KLF11. AA range:1-50
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 55kD
Human Gene ID 8462
Human Swiss Prot Nº O14901
Subcellular Location Nucleus .

Other Name: KLF11; FKLF; TIEG2; Krueppel-like factor 11; Transforming growth factor-beta-inducible early growth response protein 2; TGFB-inducible early growth response protein 2; TIEG-2

Background: The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],