Synphilin-1 rabbit pAb
ENT-A3767
Description
| REF | ENT-A3767 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Synphilin-1 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Synphilin-1. AA range:797-846 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 100kD |
| Human Gene ID | 9627 |
| Human Swiss Prot Nº | Q9Y6H5 |
| Subcellular Location | Cytoplasm . Detected in cytoplasmic inclusion bodies, together with SNCA. |
Other Name: SNCAIP; Synphilin-1; Sph1; Alpha-synuclein-interacting protein
Background: This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson’s disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],