SENP5 rabbit pAb
ENT-A3670
Description
| REF | ENT-A3670 |
|---|---|
| Category | Antibody Polyclonal |
| Description | SENP5 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Monkey |
| Reactivity | Human;Mouse;Monkey |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 86kD |
| Human Gene ID | 205564 |
| Human Swiss Prot Nº | Q96HI0 |
| Subcellular Location | Nucleus, nucleolus . |
Other Name: SENP5; FKSG45; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5
Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],