RhoGEF p115 rabbit pAb
ENT-A3610
Description
| REF | ENT-A3610 |
|---|---|
| Category | Antibody Polyclonal |
| Description | RhoGEF p115 rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA;IHC |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARHGEF1. AA range:162-211 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 105kD |
| Human Gene ID | 9138 |
| Human Swiss Prot Nº | Q92888 |
| Subcellular Location | Cytoplasm . Membrane . Translocated to the membrane by activated GNA13 or LPA stimulation. |
Other Name: ARHGEF1; Rho guanine nucleotide exchange factor 1; 115 kDa guanine nucleotide exchange factor; p115-RhoGEF; p115RhoGEF; Sub1.5
Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008],