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Nectin 3 rabbit pAb

Nectin 3 rabbit pAb

ENT-A3242

Description

 

 

 

REF ENT-A3242
Category Antibody Polyclonal
Description Nectin 3 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human PVRL3. AA range:184-233
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 61kD
Human Gene ID 25945
Human Swiss Prot Nº Q9NQS3
Subcellular Location Cell membrane ; Single-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane .

Other Name: PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD antigen CD113

Background: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],