Nanog P8 rabbit pAb
ENT-A3225
Description
| REF | ENT-A3225 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Nanog P8 rabbit pAb |
| Source | Rabbit |
| Applications | WB;IF;ELISA;IHC |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | WB 1:500-2000; IF/ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NANOGP8. AA range:51-100 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 35kD |
| Human Gene ID | 388112 |
| Human Swiss Prot Nº | Q6NSW7 |
| Subcellular Location | Nucleus . |
Other Name: NANOGP8; Putative homeobox protein NANOGP8
Background: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009],