MyD88 rabbit pAb
ENT-A3204
Description
| REF | ENT-A3204 |
|---|---|
| Category | Antibody Polyclonal |
| Description | MyD88 rabbit pAb |
| Source | Rabbit |
| Applications | IF;WB;IHC;ELISA |
| Reactivity | Human;Mouse;Rat;Pig |
| Reactivity | Human;Mouse;Rat;Pig |
| Dilution | IF: 1:50-200 Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunocytochemistry: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 33kD |
| Human Gene ID | 4615 |
| Human Swiss Prot Nº | Q99836 |
| Subcellular Location | Cytoplasm . Nucleus . |
Other Name: MYD88; Myeloid differentiation primary response protein MyD88
Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],