Menin rabbit pAb
ENT-A3118
Description
| REF | ENT-A3118 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Menin rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MEN1. AA range:181-230 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 67kD |
| Human Gene ID | 4221 |
| Human Swiss Prot Nº | O00255 |
| Subcellular Location | Nucleus . Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation. |
Other Name: MEN1; SCG2; Menin
Background: This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008],