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GK1 rabbit pAb

GK1 rabbit pAb

ENT-A2817

Description

 

 

 

REF ENT-A2817
Category Antibody Polyclonal
Description GK1 rabbit pAb
Source Rabbit
Applications WB;IF;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human GK. AA range:461-510
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 57kD
Human Gene ID 2710
Human Swiss Prot Nº P32189
Subcellular Location Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.

Other Name: GK; Glycerol kinase; GK; Glycerokinase; ATP:glycerol 3-phosphotransferase

Background: The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],