GAP1-InsP4 BP rabbit pAb
ENT-A2789
Description
| REF | ENT-A2789 |
|---|---|
| Category | Antibody Polyclonal |
| Description | GAP1-InsP4 BP rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse;Rat |
| Reactivity | Human;Mouse;Rat |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 95kD |
| Human Gene ID | 22821 |
| Human Swiss Prot Nº | Q14644 |
| Subcellular Location | Cell membrane. |
Other Name: RASA3; Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein
Background: This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],