Fatty Acid Synthase rabbit pAb
ENT-A2730
Description
| REF | ENT-A2730 |
|---|---|
| Category | Antibody Polyclonal |
| Description | Fatty Acid Synthase rabbit pAb |
| Source | Rabbit |
| Applications | WB;IHC;IF;ELISA |
| Reactivity | Human;Rat;Mouse; |
| Reactivity | Human;Rat;Mouse; |
| Dilution | IHC-p: 100-300.Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Fatty Acid Synthase. AA range:1478-1527 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 273kD |
| Human Gene ID | 2194 |
| Human Swiss Prot Nº | P49327 |
| Subcellular Location | Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Other Name: FASN; FAS; Fatty acid synthase
Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],