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ERCC4 rabbit pAb

ERCC4 rabbit pAb

ENT-A2704

Description

 

 

 

REF ENT-A2704
Category Antibody Polyclonal
Description ERCC4 rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse
Reactivity Human;Mouse
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 103kD
Human Gene ID 2072
Human Swiss Prot Nº Q92889
Subcellular Location Nucleus . Chromosome . Localizes to sites of DNA damage. .

Other Name: ERCC4; ERCC11; XPF; DNA repair endonuclease XPF; DNA excision repair protein ERCC-4; DNA repair protein complementing XP-F cells; Xeroderma pigmentosum group F-complementing protein

Background: The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5′ incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009],