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EKLF/CKLF/UKLF rabbit pAb

EKLF/CKLF/UKLF rabbit pAb

ENT-A2664

Description

 

 

 

REF ENT-A2664
Category Antibody Polyclonal
Description EKLF/CKLF/UKLF rabbit pAb
Source Rabbit
Applications WB;IF;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human KLF. AA range:291-340
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 38kD
Human Gene ID 10661/688/8609
Human Swiss Prot Nº Q13351/Q13887/O75840
Subcellular Location Nucleus . Colocalizes with SUMO1 in nuclear speckles. .

Other Name: KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF; KLF5; BTEB2; CKLF; IKLF; Krueppel-like factor 5; Basic transcription element-binding protein 2; BTE-binding protein 2; Colon krueppel-like factor; GC-bo

Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009],