eIF2Bγ rabbit pAb
ENT-A2657
Description
| REF | ENT-A2657 |
|---|---|
| Category | Antibody Polyclonal |
| Description | eIF2Bγ rabbit pAb |
| Source | Rabbit |
| Applications | WB;ELISA |
| Reactivity | Human;Mouse |
| Reactivity | Human;Mouse |
| Dilution | Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from eIF2Bγ . at AA range: 240-320 |
| Storage Stability | -20°C/1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band KD | 50kD |
| Human Gene ID | 8891 |
| Human Swiss Prot Nº | Q9NR50 |
| Subcellular Location | cytoplasm,cytosol,eukaryotic translation initiation factor 2B complex, |
Other Name: EIF2B3; Translation initiation factor eIF-2B subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma
Background: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],