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CNG-1β rabbit pAb

CNG-1β rabbit pAb

ENT-A2449

Description

 

 

 

REF ENT-A2449
Category Antibody Polyclonal
Description CNG-1β rabbit pAb
Source Rabbit
Applications WB;ELISA
Reactivity Human;Mouse;Rat
Reactivity Human;Mouse;Rat
Dilution Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human CNGB1. AA range:571-620
Storage Stability -20°C/1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band KD 102kD
Human Gene ID 1258
Human Swiss Prot Nº Q14028
Subcellular Location Membrane; Multi-pass membrane protein.

Other Name: CNGB1; CNCG2; CNCG3L; CNCG4; RCNC2; Cyclic nucleotide-gated cation channel beta-1; Cyclic nucleotide-gated cation channel 4; CNG channel 4; CNG-4; CNG4; Cyclic nucleotide-gated cation channel gamma; Cyclic nucleotide-gated cation channel mo

Background: In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013],